Table 2 Indications for withholding and recommencement of nebulised heparin
Nebulised heparin should be withheld if any of the following occurs: | Nebulised heparin should be recommenced if: |
|---|---|
More than 10 days have elapsed since randomisation | Having been withheld because the patient was outside the ICU, the patient returns to ICU |
The patient is outside of higher-level care setting | Having been withheld because the patient was not receiving advanced respiratory support, advanced respiratory support is reinstituted |
The patient is not receiving advanced respiratory support | Having been withheld because the APTT was unacceptably prolonged, the APTT becomes acceptable |
The treating physician deems that there is a clinically unacceptable increase in APTT (>100s) | Having been withheld because there was excessive bloodstaining of respiratory secretions, the bloodstaining of the respiratory secretions has resolved |
The treating physician deems that there is excessive bloodstaining of respiratory secretions | Having been withheld for suspected HIT, the patient is found not to have this condition |
There is pulmonary bleeding, major bleeding or suspected or confirmed HIT | Having been withheld for ECMO, the treatment with ECMO is stopped |
The patient is receiving ECMO or HFOV | Having been withheld for HFOV, the treatment with HFOV is stopped |