Table 3 Expected precision around the given safety event rate estimates in adults, toddler/infants and the whole population who will receive MRV-MNP
Event rate in sample (%) | n = 30 | n = 60 | n = 150 |
|---|---|---|---|
Event rate (%) (95% CI) | Event rate (95% CI) | Event rate (95% CI) | |
20.0 | 20.0 (9.5–37.3) | 20 (11.8–31.8) | 20.0 (14.4–27.1) |
10.0 | 10.0 (3.5–25.6) | 10 (4.7–20.2) | 10.0 (6.2–15.8) |
7.5 | 7.5 (22–22.4) | 7.5 (3.1–17.0) | 7.5 (4.3–12.9) |
5.0 | 5.0 (1.2–19.1) | 5.0 (1.7–13.7) | 5.0 (2.5–9.8) |
2.5 | 2.5 (0.3–15.4) | 2.5 (0.6–10.1) | 2.5 (1.0–6.4) |
1.0 | 1.0 (0.0–13.1) | 1.0 (0.1–7.8) | 1.0 (0.2–4.2) |