Table 1 Selection criteria

Inclusion criteria

 Patients 18 years or older diagnosed with cancer

 Patients admitted to UC Christus Clinical Hospital

 Patients reporting acute pain > or = a 4 in the Verbal Analog Scale

 Patients may present with somatic, visceral, or neuropathic pain

 Patients with prior opioid use or virgin to opioids were eligible

 Patients may be users of NSAIDs or corticosteroids

Exclusion criteria

 Patients who refuse to enter the study

 Patients who are unable to communicate in Spanish

 Altered mental status such as delirium

 Patients presenting acute liver failure or chronic liver damage Child C

 Patients with a history of allergies or hypersensitivity to acetaminophen

 Patients imminently dying or with a survival prognosis of less than 72 h

Dropout criteria

 Patients who are unable to complete assessments due to altered mental status or clinical decline

 Patients who died

 Patients who withdrew consent throughout the intervention and follow-up period