Skip to main content

Table 3 Primary and secondary outcomes

From: The effects of different surgical positions (semi-sitting and lateral position) on the surgical outcomes of large vestibular schwannoma: study protocol for a randomized controlled trial

Primary outcome

 Percentage of gross-total resection

  Extent of tumour resection

Gross total resection: total resection under the microscope, imaging without residual.

Note: The evaluation of total resection under the microscope and determination of microscopic residual tumours depend largely on subjective observations from experienced neurosurgeons according to the operation video.

Near-total resection: microscopic residual (a few tumour capsules, < 5%), imaging no residual.

Subtotal resection: microscopic residual (small tumour remnant, 5–10%), imaging small tumour remnant residual.

Partial resection: microscopic nodular residual tumour (≥ 10%), imaging nodular residual tumour.

Secondary outcomes

 Facial nerve function

As one of the inclusion criteria, facial nerve function was documented photographically at rest and while performing standardized facial expressions at defined time points (preoperatively, discharge, and 6 and 12 months after surgery).

This feature was evaluated by two experienced neurologists and classified according to the HB grading system [29].

 Hearing function

Hearing level will be analysed and evaluated using pure-tone audiometry (PTA) and speech discrimination score (SDS) according to the guidelines of the American Association of Otolaryngology–Head and Neck Surgery (AAO-HNS) classification [30].

Serviceable hearing was defined as either class A (PTA ≤ 30 dB, SDS ≥ 70%) or class B (30 < PTA ≤ 50 dB, SDS ≥ 50%) and non-serviceable hearing as class C (PTA > 50 dB, SDS ≥ 50%) or class D (any PTA, SDS < 50%).

 Surgical positioning time

  Time of operation

Craniotomy time

Intradural microsurgery time

Scalp closure surgery time

 Hospital stay

 Total hospitalization fee

  General complications

Intracranial haematoma: head imaging examination will be performed within 3 h after surgery.

Cerebrospinal fluid leakage (incision leakage or nasal leakage).

Intracranial infection: postoperative fever, cerebrospinal fluid routine, and biochemical evidence of infection.

Cranial nerve disorders in the posterior group: drinking water choking cough, articulation disorder, etc.

Others

  Special complications

VAE

Others

 Recurrence

  1. HB House-Brackmann, VAE Venous air embolism