Table 2 Predictors of time to publication
From: Publication of clinical trials on medicinal products: follow-up on trials authorized in Hungary
Time to publication in trials with available corresponding publication (n = 172) (months [mean (SE)] | Time to publication in trials completed for longer than one year (n = 232) (months [mean (SE)] | HR (95%CI)* | p | |
|---|---|---|---|---|
Trial sites | ||||
Only Europe | 34.86 (4.56) | 64.28 (5.28) | 1 | |
Also from outside Europe | 21.85 (1.31) | 35.00 (2.12) | 0.38 (0.22–0.66) | 0.001 |
Trial registration | ||||
In EU CTR only | 29.00 (9.53) | 68.14 (6.81) | 1 | |
EU CTR and clinicaltrials.gov | 22.69 (1.29) | 36.43 (2.16) | 0.24 (0.11–0.54) | 0.001 |
Participating countries | ||||
National | 42.33 (7.42) | 55.00 (11.87) | 1 | |
International | 22.57 (1.29) | 38.14 (2.08) | 0.65 (0.21–2.04) | 0.46 |
Trial design | ||||
RCT | 22.59 (1.43) | 37.87 (2.28) | 1 | |
Non-RCT | 23.28 (2.90) | 42.24 (5.27) | 1.12 (0.75–1.68) | 0.57 |
DMC | ||||
No | 27.93 (2.01) | 42.48 (2.99) | 1 | |
Yes | 17.81 (1.40) | 36.08 (3.01) | 0.85 (0.63–1.15) | 0.29 |