The Determining Effective Testing in Emergency Departments and Care Coordination on Treatment Outcomes (DETECT) for Hepatitis C (Hep C) Screening Trial: rationale and design of a multi-center pragmatic randomized clinical trial of hepatitis C screening in emergency departments

Table 3 Original assumptions used to estimate sample size and weighted and inverse probability weighted estimates from observed trial performance through April 27, 2021, and 58.6% of target enrollment

	Nontargeted screening			Targeted screening
	Original assumptions	Weighted estimates	IPW estimates	Original assumptions	Weighted estimates	IPW estimates
	%	%	%	%	%	%
Test offer	100	93.8	82.6	33	36.1	33.0
Test accept	60	26.4	33.0	60	34.0	47.0
Test complete	70	62.9	56.9	70	69.3	65.2
		HCV testing
		Original assumptions	Aggregate weighted estimates	Aggregate IPW estimates	Original assumptions
		%	%	%	%
HCV Ab+		5	5.9	4.7	10
HCV RNA+^a		65	42.4	31.1	65

ISSN: 1745-6215