Table 4 Prognostic baseline characteristics/pre-specified subgroups for analyses of the primary, secondary and exploratory outcomes

<60 years, 60 years and older. It is required at least one-third of the study population is in each category. If that condition is not met, the categories will be revised to <50 years and 50 years and older.

Female or other, male

No co-morbid disease

Presence of any of diabetes (HbA1c ≥7% and/or the consumption of glucose-lowering medication), history of cardiovascular disease, history of chronic respiratory illness, current treatment with immunosuppression or BMI ≥30kg/m² at baseline, compared with none of these factors.

Hypertension

Modified WHO score of 3 or less at randomisation

Modified WHO score of 4, 5 or 6 at randomisation