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Table 1 Recommendations for application protocol of silver diamine fluoride (SDF) solution

From: Effect of application time of 38% silver diamine fluoride solution on arresting early childhood caries in preschool children: a randomised double-blinded controlled trial protocol

Authors, year, reference

SDF application protocol

Horst et al. 2016

Journal of California Dental Association 44:16–28.

Isolate the tooth with gauze

Apply SDF to the caries of the tooth, and leave it for up to 60 s

Rinse with water

Crystal et al. 2017

Pediatric Dentistry

39:E135-E145.

Isolate the tooth with cotton rolls and/or gauze

Apply SDF to the caries of the tooth, and leave it for 60 s

Dry excess SDF with a gentle flow of compressed air

Croll & Berg 2018

Inside Dental Hygiene Continuing Education Course

(https://idh.cdeworld.com/courses/5155)

Blot-dry the surface of the carious lesion with a cotton swab and an air syringe

Paint on SDF, and continue to dab it; keep lesion isolated for 60 s

Blot with cotton swab, and then, cover it with fluoride varnish

American Dental Association 2018

(https://www.youtube.com/watch?v=a0HH7GifdM4)

Clear and dry the caries of the tooth with cotton pellet and/or gauze

Apply SDF to the caries of the tooth, and leave it for 60 s

Dry excess SDF with gauze if necessary

Yee et al. 2009

Journal of Dental Research

88:644-647.

Isolate the tooth with cotton rolls

Apply SDF to the caries of the tooth, and leave it for 120 s

Remove excess via gentle blotting with cotton pellet

Clemens et al. 2018

Journal of Public Health Dentistry

78:63-68.

Isolate the tooth with cotton rolls and/or gauze

The exposure time of SDF treatment is aimed at 120 s

Remove excess SDF with gauze, and then, apply fluoride varnish

Seifo et al. 2020

British Dental Journal

228:75-81.

Isolate the tooth with cotton rolls

Apply SDF to the caries of the tooth, and leave it for 120 s

Remove excess via gentle blotting with cotton pellet

Llodra et al. 2005

Journal of Dental Research

84:721-724.

Isolate the tooth with cotton rolls

Apply SDF to the caries of the tooth, and leave it for 180 s

Wash with a 30s water spray three minutes after the application

Burgette et al. 2019

Journal of Dentistry for Children

86:32-39.

Isolate the tooth with cotton rolls and/or gauze

Apply SDF to the caries of the tooth, and leave it for 180 s

Dry excess SDF, and then, apply fluoride varnish