Table 6 Surgical timing studies
Author | Year | Study type | Centre(s) | Number | Population | Intervention | Control | Primary outcome | Surrogate vs patient-centred | LFU (days) |
|---|---|---|---|---|---|---|---|---|---|---|
Rutan et al. [106] | 1986 | Pseudo RCT | 1 | 13 | TBSA > 50% | Early E&G | Conservative management | Basal metabolism | Surrogate | 30 |
Sorensen [107] | 1979 | Pseudo RCT | 1 | 108 | Adult and paediatric patients mostly TBSA > 40% | Early E&G | Surgery 10–14 days post injury | Mortality | Patient-centred | NA |
Guo et al. [108] | 1995 | CSWCC | 1 | 50 | TBSA > 20% | Early E&G | Standard surgical timing (4 days post burn) | Haemodynamic parameters | Surrogate | > 40 |
Kisslaogglu et al. [109] | 1997 | CSWCC | 1 | 54 | Adult and paediatric TBSA 40–80% | Early E&G | Late surgery or conservative management | Mortality | Patient-centred | 180 days (6 months) |
Puri et al. [110] | 2016 | CSWCC | 1 | 20 | TBSA > 20% | Early E&G | Conservative management | Blood loss | Surrogate | 42 |