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Table 2 Participant recruitment in each region of the UK

From: Recruitment to a large scale randomised controlled clinical trial in primary care: the Helicobacter Eradication Aspirin Trial (HEAT)

Region Total letters sent Total reply slips received Total expressions of interest (EOI) EOI as a percentage of letters sent Total1 consented participants Consented participants as a percentage of EOI Total H. pylori-positive participants H. pylori-positive participants as a percentage of consented participants
England
 CRN E Midlands 20,242 8333 4051 20.0 3531 87.2 664 18.8
 CRN Yorks & Humber 20,651 8306 4148 20.1 3023 72.9 606 20.0
 CRN Wessex 19,070 8784 4250 22.3 3386 79.7 506 14.9
 CRN Thames Valley & S Mids 9485 3946 2166 22.8 1698 78.4 249 14.7
 CRN SW Peninsula 14,609 6511 3131 21.4 2631 84.0 418 15.9
 CRN Eastern 14,732 6857 3728 25.3 2699 72.4 401 14.9
 CRN W of England 13,248 5899 2885 21.8 2384 82.6 321 13.5
 CRN NE & N Cumbria 8030 3142 1486 18.5 1154 77.7 283 24.5
 CRN W Midlands 29,953 11,353 5046 16.8 4242 84.1 772 18.2
 CRN Kent, Surrey, Sussex 9909 4723 2417 24.4 1653 68.4 256 15.5
 CRN NW Coast 10,697 3604 1932 18.1 1312 67.9 305 23.2
 CRN S London 3112 912 555 17.8 376 67.7 75 19.9
 CRN N Thames 4314 1453 793 18.4 573 72.3 123 21.5
 CRN NW London 974 252 134 13.8 80 59.7 26 32.5
 CRN GTR Manchester 1897 592 284 15.0 222 78.2 53 23.9
Total in England 180,923 74,667 37,006 20.5 28,964 78.3 5058 17.5
Wales
 Betsi Cadwaladr University LHB 1470 620 376 25.6 229 60.9 49 21.4
 Cardiff and Vale University LHB 1118 453 223 19.9 155 69.5 43 27.7
 Abertawe Bro Morgannwg University LHB 1277 595 373 29.2 242 64.9 50 20.7
 Powys Teaching LHB 427 214 134 31.4 83 61.9 17 20.5
 Aneurin Bevan LHB 816 270 157 19.2 104 66.2 31 29.8
 Cwm Taf LHB 723 283 137 18.9 102 74.5 30 29.4
 Hywel Dda LHB 209 62 35 16.7 28 80.0 9 32.1
Total in Wales 6040 2497 1435 23.8 943 65.7 229 24.3
Northern Ireland
 Belfast HSCT 88 29 26 29.5 25 96.2 6 24.0
 Southeastern HSCT 609 181 119 19.5 107 89.9 28 26.2
 Northern HSCT 305 111 69 22.6 68 98.6 20 29.4
Total in Northern Ireland 1002 321 214 21.4 200 93.5 54 27.0
Scotland
 Tayside2 LHB 261 71 23 8.8 6 26.1 0 0.0
 Lanarkshire LHB 649 198 93 14.3 53 57.0 23 43.4
Total in Scotland 910 269 116 12.7 59 50.9 23 39.0
Total in UK 188,875 77,754 38,771 20.5 30,166 77.8 5364 17.8
  1. 1A consented participant was defined as one with a valid signed Informed Consent Form and a Data Capture Record form completed at screening and entered on the HEAT database
  2. 2Tayside LHB withdrew from the trial shortly after starting recruitment due to staffing problems