Effects of Bushen-Jiangya granules on blood pressure and pharmacogenomic evaluation in low-to-medium-risk hypertensive patients: study protocol for a randomized double-blind controlled trial

Table 2 Schedule of the data collection

Process/item	Run-in period	Run-in period	Pre-treatment	Treatment period
Time point	− 7 day	− 1 day	0 days	2 weeks	4 weeks	6 weeks	8 weeks
Baseline information
Informed consent	√
Eligibility screen			√
Medical history	√
Allocation	√
Effectiveness observation
Blood pressure	√		√	√	√	√	√
24-h blood pressure			√				√
Pro-inflammatory/anti-inflammatory cytokines			√				√
Improvement in TCM syndrome			√	√	√	√	√
Improvement in quality of life			√				√
Pharmacogenomic evaluation			√				√
Safety observation
Physical exam		√					√
Blood pressure		√					√
Routine blood test		√					√
Routine urine test		√					√
Liver and kidney function		√					√
Adverse event				√	√	√	√
Other work
CRF audit							√

ISSN: 1745-6215