Table 1 Components and dose of BSJY
Chinese name | English name | Latin name | Origin | Main ingredients | Main pharmacological effects | Raw drug weight (g) | Granule weight (g) |
|---|---|---|---|---|---|---|---|
Duzhong | Eucommia bark | Cortex Eucommiae Ulmoidis | The bark of Cortex Eucommiae Ulmoidis | Quercetin; Mairin; beta-sitosterol; kaempferol; Erythraline; Eucommin A; (-)-Tabernemontanine; cyclopamine; GBGB; helenalin | Lowering BP [16]; reversing hypertensive vascular remodeling and hypertensive cardiac remodeling [17]; improving insulin resistance and lowering blood glucose [18] | 10 | 0.48 |
Dihuang | Rehmannia | Radix Rehmanniae Glutinosae | The root of Radix Rehmanniae Glutinosae | EIC; sitosterol; stigmasterol; aeginetic acid; jioglutin D; rehmaglutin B | Lowering BP and improving insulin resistance [19] glucose metabolism, lipid metabolism [20] | 25 | 3.57 |
Tianma | Gastrodia | Gastrodiae Rhizoma | The tuber of Gastrodiae Rhizoma | Daucosterol; citronellal; dauricine; gastrodin; p-hydroxybenzaldehyde; p-hydroxybenzyl alcohol; 4-hydroxybenzylamine; suchilactone; suffruticoside a; sucrose; vanillin; vanillin acetate | Impairing vascular endothelial function [21]; lowering BP [22]; improving lipid metabolism and insulin resistance [23] | 20 | 1.82 |
Wuzhuyu | Cornus fruit | Corni Fructus | The fruit of Corni Fructus | Beta-sitosterol; sitosterol; stigmasterol; mandenol; ethyl linolenate; poriferast-5-en-3beta-ol; ethyl oleate (NF); leucanthoside; hydroxygenkwanin; telocinobufagin; gemin D; tetrahydroalstonine | Regulating adipogenesis [24]; lowering blood glucose and insulin resistance [25]; improving lipid metabolism [26]; protecting vascular endothelial cell [27] and protecting target organs and tissue related to diabetic damage [28] | 10 | 1.43 |
Mudanpi | Cortex of the Peony Tree Rote | Cortex Radicis Moutan | The root and bark of Cortex Radicis Moutan | Quercetin; Mairin; sitosterol; kaempferol | Increasing the arterial blood flow, and improving glucose metabolism [29]; lowering BP and heart rate [30] | 10 | 0.91 |
Zexie | Alisma | Rhizoma Alismatis | The rhizome of Rhizoma Alismatis | Sitosterol; alisol B; alisol B monoacetate; alisol,b,23-acetate; alisol B; alisol C; alisol C monoacetate; 1-monolinolein | Lowering blood glucose [31]; improving Hepatic lipid deposition [32]; improving lipid metabolism [33] | 30 | 2.73 |
Sanqi | Notoginseng root | Notoginseng Radix | The root of Notoginseng Radix | Quercetin; beta-sitosterol; stigmasterol; mandenol; DFV; ginsenoside rh2; ginsenoside f2 | Protecting the vascular endothelium [34]; improveing myocardial ischemia [35] | 3 | 1.5 |
Shanzha | Crataegus fruit | Crataegi Fructus | The fruit of Crataegi | Quercetin; isorhamnetin; sitosterol; kaempferol; stigmasterol | Promoting anti-atherosclerosis [36]; improving vascular endothelial dysfunction [37] | 30 | 4.29 |