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Table 3 Results of power calculations to test for 1.8-fold differences in geometric mean concentrations of serotype-specific IgG concentrations

From: Pneumococcal conjugate vaccination schedules in infants—acquisition, immunogenicity, and pneumococcal conjugate and yellow fever vaccine co-administration study

Power for overall conclusion (1.8-fold difference)

99%

Power for serotype-specific conclusions

1

> 99%

3

> 99%

4

93%

5

93%

6A

86%

6B

95%

7F

> 99%

9V

> 99%

14

98%

18C

97%

19A

93%

19F

92%

23F

92%