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Fig. 1 | Trials

Fig. 1

From: Safety and efficacy of C1-inhibitor in traumatic brain injury (CIAO@TBI): study protocol for a randomized, placebo-controlled, multi-center trial

Fig. 1

Contact, complement, coagulation, and fibrinolytic systems and targets of C1-INH. Abbreviations: MAC, membrane attack complex; HMWK, high-molecular-weight kininogen; C1-INH, C1-inhibitor; t-PA, tissue plasminogen activator; MASPs, mannose-associated serine protease. Explanation: C1-INH is directed at all three pathways of the complement system, but has also an effect on the contact, fibrinolytic, and coagulation system

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Trials

ISSN: 1745-6215