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Table 3 Equivalent dose in 2-Gy fractions (EQD2) and biologically effective dose (BED) calculations

From: Salvage hypofractionated accelerated versus standard radiotherapy for the treatment of biochemical recurrence after radical prostatectomy (SHARE): the protocol of a prospective, randomized, open-label, superiority, multi-institutional trial

  Conventionally fractionated (66 Gy in 33 fractions) Hypofractionated (65 Gy in 26 fractions)
EQD2a (Gy)
 Prostate cancer 66 74.29
 Early-responding normal tissue 66 67.71
 Late-responding normal tissue 66 71.5
BEDa (Gy)
 Prostate cancer 154 173.33
 Early-responding normal tissue 79.2 81.25
 Late-responding normal tissue 110 119.17
  1. aα/β ratio for prostate cancer is 1.5, 10 for early-responding normal tissue, and 3 for late-responding normal tissue