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Fig. 1 | Trials

Fig. 1

From: Omega-3 mechanism of action in inflammation and endoplasmic reticulum stress in mononuclear cells from overweight non-alcoholic fatty liver disease participants: study protocol for the “Brazilian Omega Study” (BROS)—a randomized controlled trial

Fig. 1

Experimental interventions scheme and detailed subject flow. A After the screening and randomization period, the selected participants will be fasting for 12 h. At the hospital service, body composition will be carried out, followed by the blood collection for biochemical and mass spectrometry analysis. Immediately, participants will take their placebo or ω3 capsules and wait for 3 h. Anthropometric measurements will then be performed, the same collections will be repeated, and another part of the blood will be separated to an immunoprecipitation test to verify the association between GPR120 and βarr2 proteins. After 30 days of supplementation, all measurements will be repeated with the inclusion of immunoblot blood tests and polymorphic GPR120 gene analysis. B Detailed flow through the study. ω3 Omega-3. IPAQ International Physical Activity Questionnaire

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