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Table 2 Follow-up plan

From: Photodynamic therapy for synovial hyperplasia in patients with refractory rheumatoid arthritis: a study protocol for a randomized, double-blind, blank-controlled prospective trial

Follow-up time

Evaluation index

Baseline

UCSS, clinical evaluation of knee joints, DAS28, antibody levels, inflammation indicators, X-ray, routine blood test, routine urine test, blood biochemical test, infectious disease screening

W0

(first operation)

Pathological biopsies of synovial tissue

W4±3 d

(second operation)

UCSS, clinical evaluation of knee joints, DAS28, antibody levels, inflammation indicators, pathological biopsies of synovial tissue

W8±3 d

UCSS, clinical evaluation of knee joints, DAS28, antibody levels, inflammation indicators, blood biochemical test

W24±5 d

UCSS, clinical evaluation of knee joints, DAS28, antibody levels, inflammation indicators

W48±5 d

UCSS, clinical evaluation of knee joints, DAS28, antibody levels, inflammation indicators, X-ray

  1. W week, d days