Table 3 Biochemical parameters [mean (SD)] of the study group and control group before and after treatment

 BUN (7.0–21 mg/dL)

12.08 (3.96)

9.73 (2.41)

11.68 (3.66)

10.86 (2.14)

 Creatinine (0.9–1.3 mg/dL)

0.99 (0.12)

0.89 (0.11)

0.94 (0.18)

0.98 (0.16)

 Bicarbonate (22–29 mmol/L)

22.19 (0.79)

22.19 (0.50)

22.71 (0.94)

21.97 (0.83)

 Chloride (98–107 mmol/L)

97.98 (2.89)

98.43 (2.47)

98.32 (3.36)

98.94 (3.79)

 Potassium (3.5–5.1 mmol/L)

4.21 (0.49)

4.51 (0.47)

4.69 (0.51)

4.25 (0.55)

 Sodium (136–145 mmol/L)

142.88 (2.8)

140.49 (1.88)

141.59 (3.38)

141.14 (2.66)

 SGOT* (5–40 U/L)

33.05 (25.53–47.70)

27.65 (22.32–33.25)

26 (23.27–30.95)

26.15 (22.55–31.52)

 SGPT* (5–41 U/L)

37.75 (22.60–52.15)

29.60 (20.70–41.15)

23 (16–31.92)

27.85 (21.85–37.87)

 Alkaline phosphatase (53–128 U/L)

74.26 (17.68)

76.71 (19.63)

89.45 (18.35)

86.68 (21.18)

 Albumin (3.5–5.2 gm/dL)

4.34 (0.19)

4.32 (0.19)

4.27 (0.20)

4.31 (0.21)

 Globulin (2.3–3.6 gm/dL)

3.33 (0.31)

3.29 (0.27)

3.49 (0.39)

2.71 (0.41)

 AG ratio (1.1–2.2)

1.31 (0.16)

1.32 (0.11)

1.23 (0.14)

1.62 (0.21)

 Total protein (6.0–8.0 gm/dL)

7.67 (0.31)

7.59 (0.38)

7.77 (0.37)

7.03 (0.44)

 GGT* (< 55 U/L)

27.65 (19.33–40.40)

28.05 (22.22–35.60)

27.95 (21.40–41.02)

25 (20.57–43.92)

 Total bilirubin (0.1–1.2 mg/dL)

0.81 (0.34)

0.80 (0.33)

0.48 (0.15)

0.50 (0.16)

 Bilirubin direct (0.0–0.3 mg/dL)

0.25 (0.07)

0.22 (0.05)

0.16 (0.04)

0.16 (0.03)

 Bilirubin indirect (0.1–1.0 mg/dL)

0.55 (0.27)

0.59 (0.27)

0.32 (0.12)

0.33 (0.13)

 HbA1c

5.93 (1.65)

5.99 (1.66)

6.69 (2.29)

6.68 (2.23)

 CRP* (≤ 6 mg/L)

3.97 (1.6–6.5)

1.60 (1.0–5.32)

4.05 (1.45–7.4)

2 (1.15–4.25)

 Total RBC count (4.2–5.4 mill/cu.mm)

5.14 (0.52)

5.05 (0.49)

4.87 (0.55)

4.67 (0.56)

 Total leukocyte count (4000–11,000 cells/cu.mm)

6667.33 (2071)

7277.03 (1419.75)

7000.00 (1866.56)

8167.33 (1629.38)

 Neutrophils (40–75%)

57.09 (10.33)

59.50 (6.91)

50.15 (8.40)

52.81 (6.66)

 Lymphocytes (20–45%)

33.68 (8.77)

32.26 (6.86)

40.19 (7.45)

38.22 (6.66)

 Eosinophils* (01–06%)

1.6 (0.75–2.9)

2.3 (1.10–3.22)

1.7 (0.70–2.9)

1.8 (1.37–2.62)

 Basophils (00–02%)

0.4 (0.2)

0.26 (0.14)

0.38 (0.11)

0.15 (0.06)

 Monocytes (01–10%)

6.24 (1.78)

5.40 (1.24)

7.09 (1.71)

6.37 (1.24)

 Absolute neutrophil count (1.5–6.6 × 10³/μL)

3.94 (1.76)

4.32 (1.10)

3.57 (1.30)

4.31 (1.03)

 Absolute lymphocyte count (1.5–3.5 × 10³/μL)

2.13 (0.54)

2.29 (0.52)

2.76 (0.77)

3.11 (0.83)

 Absolute eosinophil count* (0.04–0.44 × 10³/μL)

0.11 (0.04–0.16)

0.15 (0.08–0.24)

0.12 (0.04–0.18)

0.15 (0.10–0.23)

 Absolute basophil count (< 0.2 × 10³/μL)

0.02 (0.01)

0.02 (0.01)

0.02 (0.01)

0.02 (0.01)

 Absolute monocyte count (< 1.0 × 10³/μL)

0.39 (0.09)

0.38 (0.09)

0.49 (0.18)

0.52 (0.16)

 Platelet count (150–450 × 10³/μL)

274.53 (80.13)

315.60 (81.41)

298.30 (69.65)

303.33 (86.00)

 PCT (0.18–0.28%)

0.27 (0.07)

0.31 (0.07)

0.29 (0.06)

0.28 (0.07)

 MPV (8.0–13.3 fL)

10.14 (0.99)

10.41 (1.18)

10.12 (1.14)

9.38 (0.74)

 Hemoglobin (12.5–16.0 g/dL)

14.54 (1.56)

14.37 (1.47)

13.61 (1.85)

13.43 (1.84)

 MCH (27–32 pg)

28.38 (2.95)

28.57 (2.74)

27.98 (3.33)

28.84 (3.49)

 MCHC (32–36 g/dL)

32.75 (1.56)

33.79 (0.98)

32.85 (1.32)

34.71 (1.18)

 MCV (78–100 fL)

86.49 (6.48)

84.43 (6.63)

85.02 (7.85)

82.98 (8.16)

 PCV (37–47%)

44.33 (3.83)

42.47 (3.82)

41.33 (4.90)

38.66 (4.75)

 RDW-CV (11.5–16.0 %)

14.09 (1.72)

13.24 (1.57)

14.13 (1.83)

13.34 (1.96)

 RDW-SD (39–46 fL)

42.4 (3.46)

39.05 (4.12)

41.86 (5.53)

38.50 (5.27)