Table 1 Overview of the study design

From: Targeting autonomic flexibility to enhance cognitive training outcomes in older adults with mild cognitive impairment: study protocol for a randomized controlled trial

	Enrollment	Allocation	Post-allocation																		Close-out
Timepoint	*-1m*	0	1m	2m	3m	4m	5m	6m	7m	8m	9m	*10m*	*11m*	*12m*	*13m*	*14m*	*15m*	*16m*	*17m*	*18m*	*19m*
Enrolment	X
Eligibility screen	X
Informed consent	X
Allocation		X
Interventions
RFB+VSOP			X	X	X	X	X	X				X						X
IR+VSOP			X	X	X	X	X	X				X						X
IR only			X	X	X	X	X	X				X						X
Assessments
ANS flexibility		X							X						X						X
Cognition		X							X						X						X
NPS		X							X						X						X
IADL		X							X						X						X
Neurodegeneration markers		X							X						X^a						X

Note. ^aBlood will not be collected during this point

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ISSN: 1745-6215

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