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Fig. 2 | Trials

Fig. 2

From: Effects of autonomic nervous system activation on endothelial function in response to acute exercise in hypertensive individuals: study protocol for a randomized double-blind study

Fig. 2

Schedule of enrolment, interventions, and assessment. Adapted from SPIRIT Figure 2013. **Subjects will be allocated to perform twice (X-X) each exercise session on alpha-1 adrenergic block and placebo conditions. IPAq: International Physical Activity Questionnaire; BP: blood pressure; 1-RM: one-repetition maximum; BFV: blood flow velocity; DBA: diameter of brachial artery; FMD: flow-mediated dilation; ANS: autonomic nervous system. Study period: -t1, on-site screening (at Instituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de Cardiologia – ICFUC), media postings, and patient databases; -t2, first visit of the volunteer to the research (ICFUC); -t3, second visit of the volunteer to the research (ICFUC); 0, contact with the independent researcher not involved with the study for volunteer randomization access; t1: pre-exercise assessments (10 min); t2, t3, t4: post-exercise session evaluation (10, 40, 70 min)

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