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Table 5 Exploratory secondary outcomes

From: Comparison of iguratimod and conventional cyclophosphamide with sequential azathioprine as treatment of active lupus nephritis: study protocol for a multi-center, randomized, controlled clinical trial (iGeLU study)

 

Exploratory secondary outcomes

1

Proportion of participants with complete renal remission by 52 weeks

2

Time to renal remission.

3

Duration of remission.

4

Duration of flare.

5

24-h urinary protein levels

6

Proportion of participants with double serum creatinine level and time to double serum creatinine.

7

Proportion of participants with end-stage renal disease (ESRD) and time to ESRD.

8

Proportion of participants with extrarenal flare.

9

Proportion of participants with remission defined by SLE responder index (SRI) by 24 weeks and 52 weeks.

10

Proportion of participants with positive anti-dsDNA or antibody titer.

11

Complement 3 and complement 4 levels.

12

Serum Immunoglobulin levels.