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Table 5 MRI acquisition parameters

From: The Brain in Motion II Study: study protocol for a randomized controlled trial of an aerobic exercise intervention for older adults at increased risk of dementia

Sequence

Repetition time (ms)

Echo time (ms)

Voxel size (mm3)

Band-width (kHz)

Others

Scan duration (min:s)

T1w (inversion-recovery prepared fast spoiled gradient echo)

6.7

2.9

1.0 × 1.0 × 1.0

31.25

Inversion time = 650 ms, 2× acceleration

5:31

T2-FLAIR

10,000

140

0.9 × 0.9 × 3.0

31.25

Inversion time = 2250 ms, 3 segments

5:01

Diffusion (spin-echo echo planar imaging)

8000

65

2.2 × 2.2 × 2.2

250.00

2× acceleration, 30 directions b-value = 1000, 3 b-value = 0 images

4:32

BOLD (echo planar imaging): resting state and CVR

2286

30

3.5 × 3.5 × 3.5

83.33

2x acceleration, 5:00 rest, 2:00 hypercapnia, 1:11 rest

8:11

pCASL (fast spin echo stack-of-spirals): resting perfusion

4786

10.2

3.6 × 3.6 × 5.0

62.50

Label duration = 1500 ms, post-label delay = 2025 ms, 2 averages

3:21

Dual echo pCASL: simultaneous BOLD and perfusion CVR

4000

12.7/28

3.75 × 3.75 × 3.8

250.00

Label duration = 1600 ms, post-label delay = 1000 ms, 2:16 rest, 2:00 hypercapnia, 2:00 rest

6:16

  1. Abbreviations: FLAIR, weighted fluid attenuated inversion recovery; BOLD, resting-state blood oxygen level dependent; CVR, cerebrovascular reactivity; pCASL, pseudo-continuous arterial spin labelling