Table 2 Schedule of physiological, cognitive, psychological, and neuroimaging assessments for the Brain in Motion II trial
Assessment measure | Screening assessments | Visit (months) | |||
|---|---|---|---|---|---|
0 | 3 | 6 | 18 | ||
Screening | |||||
 Telephone Interview for Cognitive Status – Modified (TICS-m) | ✓ | ||||
 Montreal Cognitive Assessment (MoCA) | ✓ | ||||
 Medical history | ✓ | ||||
 Demographics and health history | ✓ | ||||
 Eligibility screening questionnaire | ✓ | ||||
 Physical Activity Readiness Questionnaire (PAR-Q+) | ✓ | ||||
 Brain Injury Screening Questionnaire (BISQ) | ✓ | ||||
 Sociodemographic questionnaire | ✓ | ||||
 Vital signs | ✓ | ✓ | ✓ | ✓ | |
Cognition | |||||
 Neuropsychological test battery | ✓ | ✓ | ✓ | ||
Cerebral blood flow | |||||
 Transcranial Doppler ultrasound | ✓ | ✓ | ✓ | ||
Maximal aerobic oxygen uptake | |||||
 Maximal aerobic capacity test | ✓ | ✓ | ✓ | ||
Blood biomarkers | |||||
 Blood work | ✓ | ✓ | ✓ | ||
Genetic risk factors | ✓ | ||||
Risk/protective factors | |||||
 Global Physical Activity Questionnaire (GPAQ) | ✓ | ✓ | ✓ | ||
 Diet History Questionnaire | ✓ | ✓ | ✓ | ||
 Memory Assessment Clinic Questionnaire (MAC-Q) | ✓ | ✓ | ✓ | ✓ | |
 Multiple Ability Self-Report Questionnaire (MASQ) | ✓ | ✓ | ✓ | ||
 Lifetime Cognitive Activities Questionnaire | ✓ | ||||
 Current Cognitive Activities Questionnaire | ✓ | ✓ | ✓ | ||
 Clinical Dementia Rating Scale (CDRS) | ✓ | ✓ | |||
 Lubben Social Network Scale | ✓ | ✓ | ✓ | ||
 Family and Friend Support for Exercise | ✓ | ✓ | ✓ | ||
 Physical activity-related autonomy support, persuasion, and pressure | ✓ | ✓ | ✓ | ||
 Motivation for leisure time physical activity (BREQ-3) | ✓ | ✓ | ✓ | ||
 Adult ADHD Self-Report Questionnaire (ASRS) | ✓ | ✓ | ✓ | ||
 Hospital Anxiety and Depression Scale (HADS) | ✓ | ✓ | ✓ | ||
 Geriatric Depression Scale (GDS) | ✓ | ✓ | ✓ | ||
 Centres for Epidemiological Studies Depression Inventory | ✓ | ✓ | ✓ | ||
 Beck Anxiety Inventory (BAI) | ✓ | ✓ | ✓ | ||
 Perceived Stress Scale Questionnaire (PSS) | ✓ | ✓ | ✓ | ||
 Anxiety Sensitivity Index (ASI) | ✓ | ✓ | ✓ | ||
Sleep quality | |||||
 Polysomnography and actigraphy | ✓ | ✓ | ✓ | ||
 Sleep quality/daytime sleepiness/sleep disorders | ✓ | ✓ | ✓ | ||
 Pittsburgh Sleep Quality Index (PSQI) | ✓ | ✓ | ✓ | ||
 Epworth Sleepiness Scale (ESS) | ✓ | ✓ | ✓ | ||
 STOP-Bang | ✓ | ✓ | ✓ | ||
 Insomnia Severity Index (ISI) | ✓ | ✓ | ✓ | ||
 Restless Legs Questionnaire | ✓ | ✓ | ✓ | ||
Health behaviour | |||||
 Motivational Readiness Questionnaire | ✓ | ✓ | ✓ | ||
 Exercise Benefits/Barriers Scale | ✓ | ✓ | ✓ | ||
 EuroQoL Five-Dimension Quality of Life Scale (EQ-5D-5L) | ✓ | ✓ | ✓ | ||
 Exercise Self-Efficacy Scale (EXSE) | ✓ | ✓ | ✓ | ||
 Adherence Intent and Self-Regulatory Processes Scale | ✓ | ✓ | ✓ | ||