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Table 6 Overview of blood sampling volumes during the study

From: IMI2-PainCare-BioPain-RCT3: a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by electroencephalography (EEG)

 

Volume / sample (mL)

Number of samples

Total volume (mL)

Screening visit

6

1

6

Optional visit

6

1

6

Pharmacokinetics:

 Period 1

6

5

30

 Period 2

6

5

30

 Period 3

6

5

30

 Period 4

6

5

30

Maximum total volume of blood per subject (mL):

  

132