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Fig. 3 | Trials

Fig. 3

From: Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults

Fig. 3

Power of the trial to detect different effect sizes (treatment effect odds ratios) in the primary outcome with enrollment of 1000 participants. The primary outcome is the COVID-19 7-point Ordinal Clinical Progression Scale, analyzed with a cumulative probability model. An odds ratio < 1.0 indicates more favorable clinical outcomes on the scale in the convalescent plasma group than the placebo group. With enrollment of 1000 participants, the trial has power to detect on odds ratio ≤ 0.73

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