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Table 1 Magnetic resonance imaging protocol

From: Reshaping the path of vascular cognitive impairment with resistance training: a study protocol for a randomized controlled trial

 

3D T1-w MPRAGEa

3D T2-w

PD-w

DWIb

GRASE

rs-fMRI

Resolution acquired/reconstructed (mm2)

1 × 1/1 × 1

1 × 1/0.8 × 0.8

0.99 × 1/0.98 × 0.98

2.24 × 2.24/2 × 2

0.99 × 2.04/0.96 × 0.95

3 × 3/3 × 3

Slice thickness acquired/reconstructed (mm)

1/1

1.6/0.8

1/1

2.20/2.20

5/2.5

3/3

Number of reconstructed slices

170

200

170

70

40

36

Field of view ap/rl/fh (mm)

256 × 200 × 170

256 × 160 × 256

250 × 170 × 250

224 × 224 × 154

230 × 190 × 100

240 × 240 × 143

Orientation

Transverse

Sagittal

Sagittal

Transverse

Transverse

Transverse

Echo time (ms)

3.5

363

30

60

8, 16, 24 … 384

30

Repetition time (ms)

1800

2500

3000

7.1

1073

2000

Flip angle (deg)

8

90

90

90

90

90

Acquisition time (min)

6:34

4:43

10:33

7:27

7:30

5:00

Purpose

Anatomical reference

WMH quantification

WMH quantification

White matter integrity quantification

Myelin quantification

Functional connectivity assessment

  1. ap anterior-posterior, rl right left, fh foot-head
  2. aAdditional sequence parameters for 3D T1-w MPRAGE: inversion time = 810 ms
  3. bAdditional sequence parameters for DWI: 60 gradient directions at b = 700 s/mm2, 1 unweighted scan