Table 1 Summary of TCM CT records (n, %)
Category | COVID-19 (N = 129) | H1N1 (N = 7) | Total (N = 136) |
|---|---|---|---|
Registration | |||
 ChiCTR | 122 (94.6%) | 5 (71.4%) | 127 (93.4%) |
 ClinicalTrials.gov | 7 (5.4%) | 2 (28.6%) | 9 (6.6%) |
Study type | |||
 Interventional study | 107 (82.9%) | 5 (71.4%) | 112 (82.4%) |
 Observational study | 22 (17.1%) | 2 (28.6%) | 24 (17.6%) |
Primary sponsor | |||
 Hospital | 107 (82.9%) | 5 (71.4%) | 112 (82.4%) |
 University | 12 (9.3%) | N/A | 12 (8.8%) |
 Others | 10 (7.8%) | 2 (28.6%) | 12 (8.8%) |
Intervention | |||
 Chinese herbal products | 42 (32.6%) | 4 (57.1%) | 46 (33.8%) |
 TCM treatment | 16 (12.4%) | 3 (42.9%) | 19 (14.0%) |
 Chinese herbal formula | 40 (31.0%) | N/A | 40 (29.4%) |
 Integration of traditional Chinese and Western medicine | 11 (8.5%) | N/A | 11 (8.1%) |
 Nonpharmaceutical treatment of TCM | 8 (6.2%) | N/A | 8 (5.9%) |
 Others | 12 (9.3%) | N/A | 12 (8.8%) |
Assignment | |||
 Parallel | 81 (62.8%) | 5 (71.4%) | 86 (63.2%) |
 Sequential | 15 (11.6%) | N/A | 15 (11.0%) |
 Single arm | 7 (5.4%) | N/A | 7 (5.1%) |
 Factorial | 2 (1.6%) | N/A | 2 (1.5%) |
 Others | 5 (3.9%) | 2 (28.6%) | 7 (5.1%) |
 Not reported | 19 (14.7%) | N/A | 19 (14.0%) |
Method of allocation | |||
 Randomized | 83 (64.3%) | 5 (71.4%) | 88 (64.7%) |
 Non-randomized | 45 (34.9%) | 2 (28.6%) | 47 (34.6%) |
 Quasi-randomized | 1 (0.8%) | N/A | 1 (0.7%) |
Masking | |||
 Quadruple blind | 1 (0.7%) | N/A | 1 (0.7%) |
 Triple blind | 1 (0.7%) | N/A | 1 (0.7%) |
 Double blind | 8 (6.2%) | 1 (14.3%) | 9 (6.6%) |
 Open label | 36 (27.9%) | 1 (14.3%) | 37 (27.2%) |
 Not reported | 83 (64.3%) | 5 (71.4%) | 88 (64.7%) |
Recruitment status | |||
 Pending | 58 (45.0%) | N/A | 58 (42.6%) |
 Recruiting | 68 (52.7%) | 3 (42.9%) | 71 (52.2%) |
 Suspended | 2 (1.6%) | N/A | 2 (1.5%) |
 Completed | 1 (0.8%) | 4 (57.1%) | 5 (3.7%) |
Prospective and retrospective registration | |||
 Retrospective | 19 (14.7%) | N/A | 19 (14.0%) |
 Prospective | 110 (85.3%) | 7 (100.0%) | 117 (86.0%) |
IPD sharing plan | |||
 Yes | 119 (92.2%) | 6 (85.7%) | 125 (91.9%) |
 No | 3 (2.3%) | N/A | 3 (2.2%) |
 N/A | 7 (5.4%) | 1 (14.3%) | 8 (5.9%) |