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Table 1 Summary of TCM CT records (n, %)

From: Calling for improved quality in the registration of traditional Chinese medicine during the public health emergency: a survey of trial registries for COVID-19, H1N1, and SARS

Category COVID-19 (N = 129) H1N1 (N = 7) Total (N = 136)
Registration
 ChiCTR 122 (94.6%) 5 (71.4%) 127 (93.4%)
 ClinicalTrials.gov 7 (5.4%) 2 (28.6%) 9 (6.6%)
Study type
 Interventional study 107 (82.9%) 5 (71.4%) 112 (82.4%)
 Observational study 22 (17.1%) 2 (28.6%) 24 (17.6%)
Primary sponsor
 Hospital 107 (82.9%) 5 (71.4%) 112 (82.4%)
 University 12 (9.3%) N/A 12 (8.8%)
 Others 10 (7.8%) 2 (28.6%) 12 (8.8%)
Intervention
 Chinese herbal products 42 (32.6%) 4 (57.1%) 46 (33.8%)
 TCM treatment 16 (12.4%) 3 (42.9%) 19 (14.0%)
 Chinese herbal formula 40 (31.0%) N/A 40 (29.4%)
 Integration of traditional Chinese and Western medicine 11 (8.5%) N/A 11 (8.1%)
 Nonpharmaceutical treatment of TCM 8 (6.2%) N/A 8 (5.9%)
 Others 12 (9.3%) N/A 12 (8.8%)
Assignment
 Parallel 81 (62.8%) 5 (71.4%) 86 (63.2%)
 Sequential 15 (11.6%) N/A 15 (11.0%)
 Single arm 7 (5.4%) N/A 7 (5.1%)
 Factorial 2 (1.6%) N/A 2 (1.5%)
 Others 5 (3.9%) 2 (28.6%) 7 (5.1%)
 Not reported 19 (14.7%) N/A 19 (14.0%)
Method of allocation
 Randomized 83 (64.3%) 5 (71.4%) 88 (64.7%)
 Non-randomized 45 (34.9%) 2 (28.6%) 47 (34.6%)
 Quasi-randomized 1 (0.8%) N/A 1 (0.7%)
Masking
 Quadruple blind 1 (0.7%) N/A 1 (0.7%)
 Triple blind 1 (0.7%) N/A 1 (0.7%)
 Double blind 8 (6.2%) 1 (14.3%) 9 (6.6%)
 Open label 36 (27.9%) 1 (14.3%) 37 (27.2%)
 Not reported 83 (64.3%) 5 (71.4%) 88 (64.7%)
Recruitment status
 Pending 58 (45.0%) N/A 58 (42.6%)
 Recruiting 68 (52.7%) 3 (42.9%) 71 (52.2%)
 Suspended 2 (1.6%) N/A 2 (1.5%)
 Completed 1 (0.8%) 4 (57.1%) 5 (3.7%)
Prospective and retrospective registration
 Retrospective 19 (14.7%) N/A 19 (14.0%)
 Prospective 110 (85.3%) 7 (100.0%) 117 (86.0%)
IPD sharing plan
 Yes 119 (92.2%) 6 (85.7%) 125 (91.9%)
 No 3 (2.3%) N/A 3 (2.2%)
 N/A 7 (5.4%) 1 (14.3%) 8 (5.9%)
  1. ChiCTR Chinese Clinical Trial Registry, TCM traditional Chinese medicine, COVID-19 severe acute respiratory syndrome coronavirus 2, H1N1 H1N1 influenza, N/A not available