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Table 2 Barriers identified through interviews

From: Barriers impacting the POINT pragmatic trial: the unavoidable overlap between research and intervention procedures in “real-world” research

Situation of barrier/challenge 

CFIR construct (domain)

Specific barriers/issues discussed

Source

Example quote

Intervention

Complexity (study characteristicsa)

Complexity of research protocol

PRCs

… having them [patients] sit there and be patient through all these questions [before providing services] … they are starting to get annoyed. (PRC)

Culture (inner setting)

ED staff lack SUD knowledge

PRCs, supervisors, researchers

[ED staff] were not well educated on how to work with opioid use disorder … we have actually had physicians come to our coaches asking how they should treat a patient. (Researcher)

Patient needs and resources (outer setting)

Lack of community referral resources

PRCs, supervisors, researchers

… there’s still just a disconnect between the resources [in the community], and it takes a long time to get someone in somewhere … (PRC)

Research

Personal attributes (characteristic of individuals)

PRCs are better at study recruitment

PRCs, supervisors, researchers

… the research assistants were not … being visible in that area [the ED] as what they needed to be” (supervisor)

Intervention and research

Complexity (intervention characteristics)

Timing of intervention delivery

PRCs, supervisors

… it’s inherently difficult [to speak with patients] … you deal with people who were again, highly sedated, often times. (PRC)

Networks and communication (inner setting)

Ineffective communication with ED staff

PRCs, supervisors, researchers

… [nurses] are so busy and there is so much information coming at them … there is no time for meetings throughout the day {to get] in front of them for a half hour and kind of explain what we do and who is appropriate [for the study]. (PRC)

Structure (inner setting)

ED lacks privacy

PRCs, supervisors

… a lot of our patients are in the hallway … they say the entire ED is a private area but when you are talking to someone … being asked questions about their drug use … can be a little off-putting for some people. (PRC)

Culture (inner setting)

Fast-paced ED setting

PRCs, supervisors, researchers

to get [patients] to do the study itself … they had to have a discharge order, and so you had a very tight window to get in there and engage …. (PRC)

Patient needs and resources (outer setting)

Patients’ limited resources

PRCs, researchers

… I’d have that initial intervention there in the ED and then a huge barrier was follow-up … a lot of them did not have working phones, you know there was no family support that you could contact (PRC)

  1. a“Study characteristics” is not a CFIR domain. As such, this is a parallel to CFIR “intervention characteristics” domain