Bioavailable turmeric extract for knee osteoarthritis: a randomized, non-inferiority trial versus paracetamol

Table 3 Comparison of the difference in mean change of efficacy parameters at the end of study between turmeric extract and paracetamol after baseline covariate adjustment

Domain	Group	Mean change ± SE at 6 weeks after baseline covariate adjustment	Mean difference ± SE	T	p value*
Total WOMAC	Paracetamol (n = 71)	40.71 ± 1.07	0.54 ± 1.50	0.359	0.7204
Total WOMAC	Turmeric extract (n = 73)	40.17 ± 1.05	0.54 ± 1.50	0.359	0.7204
Pain	Paracetamol (n = 71)	8.35 ± 0.33	− 0.04 ± 0.47	− 0.089	0.9293
Pain	Turmeric extract (n = 73)	8.39 ± 0.33	− 0.04 ± 0.47	− 0.089	0.9293
Stiffness	Paracetamol (n = 71)	3.29 ± 0.12	− 0.04 ± 0.17	− 0.22	0.826
Stiffness	Turmeric extract (n = 73)	3.33 ± 0.12	− 0.04 ± 0.17	− 0.22	0.826
Function	Paracetamol (n = 71)	29.19 ± 0.73	0.87 ± 1.03	0.849	0.3972
Function	Turmeric extract (n = 73)	28.32 ± 0.72	0.87 ± 1.03	0.849	0.3972
CRP	Paracetamol (n = 68)	18.83 ± 1.77	4.48 ± 2.47	1.81	0.0718
CRP	Turmeric extract (n = 72)	14.35 ± 1.72	4.48 ± 2.47	1.81	0.0718
TNF-α	Paracetamol (n = 68)	46.29 ± 7.75	28.74 ± 10.91	2.63	0.0095
TNF-α	Turmeric extract (n = 69)	17.55 ± 7.69	28.74 ± 10.91	2.63	0.0095

ISSN: 1745-6215