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Table 3 Baseline laboratory measurements of female participants included in the PREVAC trial (pooled for versions 2.0, 3.0, and 4.0)

From: Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries

Baseline laboratory measurements: females

 

Age 18+ (n = 1118 )

Age 12–17 (n = 429)

Age 5–11 (n = 353)

Age 1–4 (n = 276 )

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Biochemistry

 ALT (U/L)

10.9

10.6

9.3

7.3

11.7

11.8

13.8

38.2

 AST (U/L)

14.2

9.6

14.9

6.7

20.7

11.6

28.9

30.6

 Creatinine (mg/dl)

0.80

0.15

0.66

0.15

0.53

0.13

0.38

0.10

 Potassium (mmol/L)

4.1

0.4

4.2

0.3

4.1

0.4

4.3

0.5

Hematology

 White blood cells (x10³/μL)

6.1

2.1

6.2

1.8

7.0

1.9

8.9

2.7

 Neutrophils (x10³/μL)

2.9

1.2

2.7

1.1

2.9

1.4

3.2

1.4

 Lymphocytes (x10³/μL)

2.5

1.4

2.6

0.9

3.0

0.9

4.5

1.7

 Eosinophils (x10³/μL)

0.21

0.26

0.26

0.37

0.35

0.43

0.39

0.64

 Monocytes (x10³/μL)

0.46

0.18

0.52

0.20

0.60

0.22

0.77

0.34

 Basophils (x10³/μL)

0.08

0.10

0.08

0.04

0.10

0.05

0.15

0.09

 Hemoglobin (g/dl)

12.3

1.3

12.3

1.3

11.9

1.2

10.7

1.2

 Hematocrit (%)

37.5

3.6

37.2

3.5

36.0

3.4

33.2

3.2

 Platelets (x10³/μL)

264.2

71.7

288.4

76.4

321.4

87.2

394.3

111.0

 Red blood cells (x106/μL)

4.5

0.5

4.6

0.5

4.6

0.5

4.6

0.5

 Red cell distribution width (%)

13.3

1.6

13.3

1.6

13.6

1.6

14.9

2.3

 Mean corpuscular volume (fL)

83.8

7.0

80.9

7.3

78.1

6.4

72.8

8.0

  1. Lower limit of detection is imputed for undetectable results