Measure | Target concept | T0 | T1 | T2 |
---|---|---|---|---|
Retrospective questionnaires | ||||
 CFQ | Subjective measure of cognitive functioning | x | x | x |
 DASS | Emotional distress | x | x | x |
 CIS – subscale severity | Fatigue severity | x | x | x |
 CHIME | Mindfulness skills | x | x | x |
Neurocognitive testing | ||||
 Bourdon-Wiersma Dot Cancellation Test | Attention and concentration | x | x | x |
 Auditory Verbal Learning Test | Memory | x | x | x |
 WAIS III forward digit span | Memory | x | x | x |
 WAIS III backwards digit span | Executive functioning |  |  |  |
 WAIS III letter-number sequencing | Executive functioning | x | x | x |
 Stroop Color Word Test | Executive functioning | x | x | x |
 Controlled Oral Word Association Test | Executive functioning | x | x | x |
 WAIS digit symbol-coding | Cognitive/psychomotor processing speed | x | x | x |
 9HPT | Cognitive/psychomotor processing speed | x | x | x |
 TMT – Form A | Cognitive/psychomotor processing speed | x | x | x |
 TMT – Form B | Attention and concentration/executive functioning |  |  |  |
 DART | Verbal IQ | x | x | x |
Brain imaging | ||||
 High-resolution, T1-weighted imaging | Brain structure | x | x | x |
 Active fMRI during N-back task | Brain activation during N-back task | x | x | x |
 Resting-state fMRI | Brain connectivity | x | x | x |
 Diffusion MRI | White matter microstructure | x | x | x |
Biomarkers of inflammation | ||||
 IL-1, IL-6 and TNF-α | Inflammatory process | x | x | x |