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Table 2 Overview of measures and corresponding measurement time points

From: A mindfulness-based intervention for breast cancer patients with cognitive impairment after chemotherapy: study protocol of a three-group randomized controlled trial

Measure

Target concept

T0

T1

T2

Retrospective questionnaires

 CFQ

Subjective measure of cognitive functioning

x

x

x

 DASS

Emotional distress

x

x

x

 CIS – subscale severity

Fatigue severity

x

x

x

 CHIME

Mindfulness skills

x

x

x

Neurocognitive testing

 Bourdon-Wiersma Dot Cancellation Test

Attention and concentration

x

x

x

 Auditory Verbal Learning Test

Memory

x

x

x

 WAIS III forward digit span

Memory

x

x

x

 WAIS III backwards digit span

Executive functioning

   

 WAIS III letter-number sequencing

Executive functioning

x

x

x

 Stroop Color Word Test

Executive functioning

x

x

x

 Controlled Oral Word Association Test

Executive functioning

x

x

x

 WAIS digit symbol-coding

Cognitive/psychomotor processing speed

x

x

x

 9HPT

Cognitive/psychomotor processing speed

x

x

x

 TMT – Form A

Cognitive/psychomotor processing speed

x

x

x

 TMT – Form B

Attention and concentration/executive functioning

   

 DART

Verbal IQ

x

x

x

Brain imaging

 High-resolution, T1-weighted imaging

Brain structure

x

x

x

 Active fMRI during N-back task

Brain activation during N-back task

x

x

x

 Resting-state fMRI

Brain connectivity

x

x

x

 Diffusion MRI

White matter microstructure

x

x

x

Biomarkers of inflammation

 IL-1, IL-6 and TNF-α

Inflammatory process

x

x

x

  1. Abbreviations: T0 baseline, T1 1–3 weeks post intervention, T2 3 months post intervention, 9HPT Nine-hole Peg Test, CFQ Cognitive Failure Questionnaire, CHIME Comprehensive Inventory of Mindfulness Experiences, CIS Checklist Individual Strength, DART Dutch Adult Reading Test, DASS Depression, Anxiety, Stress Scales, fMRI functional magnetic resonance imaging, IL interleukin, MRI magnetic resonance imaging, TMT Trail Making Test, TNF tumor necrosis factor, WAIS Wechsler Adult Intelligence Test