Table 4 Empirical type 1 error (size) of the nine tests in pooled simulated samples with low or high event rates and ≤100 events in each simulation replicate
Test | Abbrev- | Low event rate | High event rate | ||
|---|---|---|---|---|---|
| Â | iation | Size | 95% CI | Size | 95% CI |
Logrank | LR | 5.2 | (4.9,5.6) | 5.5 | (5.1,5.8) |
Logrank (early) | LRE | 5.2 | (4.9,5.6) | 5.3 | (4.9,5.6) |
Logrank (late) | LRL | 4.8 | (4.5,5.2) | 6.0 | (5.6,6.3) |
Supremum logrank | SupLR | 4.3 | (4.0,4.6) | 4.5 | (4.2,4.9) |
Joint | J | 5.2 | (4.9,5.6) | 5.1 | (4.8,5.5) |
Combined | C | 5.1 | (4.7,5.4) | 5.6 | (5.2,5.9) |
Weighted combined | WC | 4.7 | (4.4,5.0) | 6.2 | (5.8,6.6) |
Versatile WLR | VWLR | 5.1 | (4.8,5.4) | 5.7 | (5.3,6.1) |
Versatile WLR (modified) | VWLR2 | 5.0 | (4.7,5.4) | 5.7 | (5.4,6.1) |