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Table 3 Empirical type 1 error (size) of the nine tests in 60,000 simulated samples for low and high event rates

From: A simulation study comparing the power of nine tests of the treatment effect in randomized controlled trials with a time-to-event outcome

Test

Abbrev.

Low event rate

High event rate

  

Size (%)

95% CI

Size (%)

95% CI

Logrank

LR

5.0

(4.8,5.2)

5.1

(4.9,5.3)

Logrank (early)

LRE

5.0

(4.8,5.2)

5.1

(5.0,5.3)

Logrank (late)

LRL

4.9

(4.7,5.1)

5.3

(5.1,5.4)

Supremum logrank

SupLR

4.5

(4.4,4.7)

4.6

(4.5,4.8)

Joint

J

5.1

(4.9,5.3)

5.0

(4.9,5.2)

Combined

C

4.9

(4.7,5.1)

5.0

(4.8,5.2)

Weighted combined

WC

4.8

(4.6,5.0)

5.4

(5.2,5.6)

Versatile WLR

VWLR

5.0

(4.8,5.2)

5.2

(5.0,5.4)

Versatile WLR (modified)

VWLR2

5.1

(4.8,5.1)

5.2

(5.0,5.4)