Table 1 Eligibility criteria

Inclusion criteria

• Listed for a primary TKR at the NNUH (may be referred to Spire Norwich for the operation)

• Indication for the TKR is primary osteoarthritis of the knee joint involving one or more compartments

• Aged 18 years or over

• Patient willing to provide full informed consent to the trial including consent for any incidental findings to be communicated to their general practitioner (GP)

Exclusion criteria

• Listed for a single-stage, bilateral TKR procedure

• Severe symptoms in the contralateral knee so as to require staged, bilateral knee replacements within 6 months of the primary procedure

• Fixed-flexion deformity of 15° or greater or patients who may require excessive resection of the distal femur

• Clinically assessed uncorrectable varus/valgus deformity of 15° or greater

• Any co-morbidity which, in the opinion of the investigator, is severe enough to present an unacceptable risk to the patient’s safety

• Inflammatory arthritis

• Previous septic arthritis in the affected knee joint

• Previous surgery to the collateral ligaments of the affected knee

• A contralateral TKR that has been implanted less than 1 year from the date of consultation, or severely painful

• Patients taking warfarin or Novel Oral Anti-Coagulants

• Will not be resident in the catchment area for NNUH for at least 6 months post surgery

• Undertaking the surgery as a private (non-NHS) patient

• Patients who, in the opinion of the clinical staff, do not have capacity to consent

• Patients who are pregnant

• Unable to understand written and spoken English

• Patients currently enrolled on an interventional trial involving surgery, exercise or rehabilitation. Patients can be co-enrolled into studies not meeting the above criteria given prior agreement from the TMG of both studies. Patients who enter the study are eligible for entry onto the National Joint Registry and in terms of the Journey II BCS, into Beyond Compliance