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Table 1 Strengths and weaknesses of human and in silico imaging clinical trials

From: In silico imaging clinical trials: cheaper, faster, better, safer, and more scalable

Human trial In silico trial
+ Real-world device usage −Approximation
− Limited samples + Unlimited samples
− Large variability + Adjustable variability
− Narrow scope + Broader scope
− Truth uncertain + Truth known exactly
− Risk to patients + No patient risk
− Burdensome + Less burdensome