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Table 2 Sample size and 95% confidence interval for successful treatment proportion of 90% and 95% among participants of the cefixime or penicillin arm

From: Clinical trial protocol to evaluate the efficacy of cefixime in the treatment of early syphilis

Sample size of evaluable subjects

Efficacy proportion of 90%

Efficacy proportion of 95%

20

68–99%

0.75, 1.0

40

76–97%

0.83, 0.99

60

79–96%

86–99%

  1. 95% confidence intervals calculated using a binomial exact test