Table 1 Baseline data collected before randomisation in the three trials

Sex

Women

N(%)

Men

N(%)

Age

Age ≤70 years

N(%)

Age >70 years

N(%)

Mean (sd)

Mean (sd)

Ethnicity

Asian

N(%)

Black

N(%)

Chinese

N(%)

White

N(%)

Other

N(%)

Marital Status

Married

N(%)

Partner

N(%)

Divorcer/separated

N(%)

Widowed

N(%)

Single

N(%)

Other

N(%)

Living arrangement

Living with someone

N(%)

Living alone

N(%)

Living in an inst.

N(%)

Other

N(%)

Employment

FT

N(%)

PT

N(%)

Retired

N(%)

Unemployed/disabled

N(%)

Other

N(%)

N(%)

Previous medical history

Coronary heart disease

N(%)

Ischaemic stroke/TIA

N(%)

Diabetes

N(%)

Hyponatraemia

N(%)

Intracranial bleed

N(%)

Upper GI bleed

N(%)

Bone fractures

N(%)

Depression

N(%)

Stroke diagnosis

Not-stroke

N(%)

Ischaemic stroke

N(%)

Intracerebral haemorrhage

N(%)

OCSP classification of Ischaemic stroke

Total anterior circulation infarct

N(%)

Partial anterior circulation infarct

N(%)

Lacunar infarct

N(%)

Posterior circulation infarct

N(%)

Uncertain

N(%)

Cause of stroke, modified TOAST classification

Large artery disease

N(%)

Small vessel disease

N(%)

Embolism from heart

N(%)

Another cause

N(%)

Unknown/uncertain

N(%)

Predictive variables

Able to walk at time of randomisation

N(%)

Able to lift both arms off bed

N(%)

Able to talk and not confused

N(%)

Predicted 6-month outcome based on SSV

Prob. of being alive and independent

Q2(Q1,q3)

0.00 to ≤ 0.15

N(%)

>0.15 to 1.00

N(%)

Neurological deficits

NIHSS

Q2(Q1,q3)

Presence of motor deficit

N(%)

Presence of aphasia

N(%)

Depression at baseline

Current diagnosis of depression

N(%)

Taking a non-SSRI antidepressant

N(%)

Current mood (PHQ-2)

2 yes responses

N(%)

1 yes response

N(%)

0 yes responses

N(%)

Delay (days) since stroke onset at randomisation

Mean (sd)

Mean (sd)

2-8 days

N(%)

9-15 days

N(%)

Details of enrolment

Enrolled as a hospital inpatient

N(%)

Patient consented

N(%)

Proxy consented

N(%)