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Fig. 2 | Trials

Fig. 2

From: Combined HIV Adolescent Prevention Study (CHAPS): comparison of HIV pre-exposure prophylaxis regimens for adolescents in sub-Saharan Africa—study protocol for a mixed-methods study including a randomised controlled trial

Fig. 2

Flow diagram of participant and foreskin journey for oral PrEP, in vitro drug exposure and ex vivo HIV challenge. The analysis group identifiers in stage 2 comprise three components: a letter indicating the stage 1 group, a number (5 or 21) indicating the interval between the last oral PrEP dose and circumcision and an item indicating in vitro dosing (where 0 = no dose). The exceptions are the group of men who did not receive oral PrEP (Group X): these groups do not include the middle component

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