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Fig. 1 | Trials

Fig. 1

From: Combined HIV Adolescent Prevention Study (CHAPS): comparison of HIV pre-exposure prophylaxis regimens for adolescents in sub-Saharan Africa—study protocol for a mixed-methods study including a randomised controlled trial

Fig. 1

Flow diagram of participant and foreskin journey for primary analysis (oral PrEP only). The numbers in the black boxes indicate the randomisation groups—there are nine, with each man allocated to exactly one group, with each group equally likely. This figure shows recruitment from both sites; recruitment will be split equally between SA (n = 72) and Uganda (n = 72). The numbers in the green boxes refer to the analysis groups. The main comparison will be between groups A–D. Group X, men who do not receive PrEP, will be used as a comparison and to ensure that the ex vivo challenge model is successful

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