A pilot protocol to assess the feasibility of a virtual multiple crossover, randomized controlled trial design using methylphenidate in mild cognitive impairment

Table 3 Outcome measures grouped by domain

	Standard measures	Daily measures
Cognitive function	RBANS Oral Trail Making Test Continuous Performance Task BVMT-R Speech production task	Lumosity games - Speed - Memory - Problem-solving - Attention - Flexibility
Neuropsychiatric symptoms	Agitated Behavior in Dementia Scale Apathy Evaluation Scale Beck Anxiety Inventory Geriatric Depression Scale	Daily mood ratings Daily sleep ratings
Functional abilities	Functional Activities Questionnaire ADCS-ADL-MCI Dementia Severity Rating Scale	Fitbit activity tracking
Physiological measures	6-lead ECG using the KardiaMobile 6L device (AliveCor, Inc.)	Fitbit heart rate tracking Fitbit sleep tracking

ISSN: 1745-6215