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Table 3 Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) diagram

From: Cognitive-behavioral family therapy as psychoeducation for adolescents with high-functioning autism spectrum disorders: Aware and Care for my Autistic Traits (ACAT) program study protocol for a pragmatic multisite randomized controlled trial

Time point**

Study period

Enrollment, May 20171

Allocation, March 2018

Post-allocation

Close-out, May 2020

0w

6w

10w

t4

etc.

Enrollment:

 Eligibility screen

X

       

 Informed consent

X

       

 Allocation

 

X

      

Interventions:

 Combination (ACAT) group

  

X

X

X

   

 TAU group

  

X

X

X

   

Assessments:

 Socioeconomic and demographic data

X

X

X

X

X

   

 Patients: AKQ-C, DSRS-C, BACEv3, EEG

X

X

X

X

X

   

 Parents: AKQ-P, SDQ, Vineland-2, Bace-v3, GHQ-12, EEG

X

X

X

X

X

   
  1. AKQ-C Autism Knowledge Quiz-Child, DSRS-C Depression Self-Rating Scale for Children, BACEv3 Barriers to Access to Care Evaluation scale version 3, EEG electroencephalogram, AKQ-P Autism Knowledge Quiz-Parents, SDQ Strengths and Difficulties Questionnaire, GHQ-12 General Health Questionnaire