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Table 3 Cognitive function at week 4 post-randomisation for mifepristone and placebo groups

From: Double-blind, placebo-controlled trial of mifepristone on cognition and depression in alcohol dependence

Test

Mifepristone (n = 11), mean (SD)

Placebo (n = 10), mean (SD)

Mean difference (95% CI)

Memory

 Paired Associates Learning (number of trials)

12.36 (3.47)

12.80 (3.22)

− 0.44 (− 3.70 to 2.83)

 Pattern Recognition Memory (% correct)

91.67 (7.45)

90.00 (13.49)

1.67 (− 9.18 to 12.51)

 Spatial Recognition Memory (% correct)

73.64 (12.86)

66.50 (17.49)

7.14 (− 8.01 to 22.28)

Executive Function

 Stockings of Cambridge (number of problems solved)

7.55 (2.54)

8.10 (1.96)

− 0.55 (− 2.76 to 1.65)

 Intra-Extra Dimensional Set Shift (number of trials)

164.82 (115.87)

117.60 (67.00)

47.22 (− 43.57 to 138.01)

 Spatial Working Memory (between errors)

53.09 (17.82)

39.00 (21.20)

14.09 (−5.15 to 33.33)

Attention and psychomotor speed

 Reaction Time, reaction (milliseconds)

350.44 (66.57)

330.51 (89.82)

19.92 (− 56.59 to 96.44)

 Rapid Visual Information Processing latency (milliseconds)

473.69 (114.84)

422.68 (134.90)

51.00 (− 75.16 to 177.17)

 Match to Sample Visual Search (% correct)

95.96 (5.60)

96.11 (6.44)

− 0.16 (− 6.08 to 5.77)