Skip to main content

Table 2 Characteristics of intervention and control participants based on cohort used for sample size estimationa

From: The OPTIMIZE patient- and family-centered, primary care-based deprescribing intervention for older adults with dementia or mild cognitive impairment and multiple chronic conditions: study protocol for a pragmatic cluster randomized controlled trial

  Total
N = 3671
Intervention
N = 1814 (49.4%)
Delayed control
N = 1857 (50.6%)
Intervention vs delayed control
p valueb
1+ Potentially inappropriate Medication N (%) 1226 (33.4%) 598 (33.0%) 628 (33.8%) 0.58
Age in years, mean (SD) 79.6 (7.4) 79.6 (7.5) 79.6 (7.3) 0.83
Female gender 2047 (55.8%) 1025 (56.5%) 1022 (55.0%) 0.37
Non-white racebN (%) 444 (13.3%) 247 (14.5%) 197 (12.0%) 0.03
 Missing race N (%) 325 (8.9%) 110 (6.1%) 215 (11.6%) < 0.001
Hispanic ethnicity N (%) 441 (12.2%) 128 (7.2%) 313 (17.1%) < 0.001
 Missing ethnicity N (%) 48 (1.3%) 25 (1.4%) 23 (1.2%) 0.71
  1. Comparisons for p values included: female vs male gender; non-white race vs white, excluding missing race; missing race vs not missing; Hispanic ethnicity vs non-Hispanic, excluding missing ethnicity; missing ethnicity vs not missing
  2. aAs of November 2018. Excluding 5+ medications limitation, total cohort = 8183 (intervention = 4049; delayed control 4134)
  3. bChi-square p values except for age (t test p value)