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Table 2 Characteristics of intervention and control participants based on cohort used for sample size estimationa

From: The OPTIMIZE patient- and family-centered, primary care-based deprescribing intervention for older adults with dementia or mild cognitive impairment and multiple chronic conditions: study protocol for a pragmatic cluster randomized controlled trial

 

Total

N = 3671

Intervention

N = 1814 (49.4%)

Delayed control

N = 1857 (50.6%)

Intervention vs delayed control

p valueb

1+ Potentially inappropriate Medication N (%)

1226 (33.4%)

598 (33.0%)

628 (33.8%)

0.58

Age in years, mean (SD)

79.6 (7.4)

79.6 (7.5)

79.6 (7.3)

0.83

Female gender

2047 (55.8%)

1025 (56.5%)

1022 (55.0%)

0.37

Non-white racebN (%)

444 (13.3%)

247 (14.5%)

197 (12.0%)

0.03

 Missing race N (%)

325 (8.9%)

110 (6.1%)

215 (11.6%)

< 0.001

Hispanic ethnicity N (%)

441 (12.2%)

128 (7.2%)

313 (17.1%)

< 0.001

 Missing ethnicity N (%)

48 (1.3%)

25 (1.4%)

23 (1.2%)

0.71

  1. Comparisons for p values included: female vs male gender; non-white race vs white, excluding missing race; missing race vs not missing; Hispanic ethnicity vs non-Hispanic, excluding missing ethnicity; missing ethnicity vs not missing
  2. aAs of November 2018. Excluding 5+ medications limitation, total cohort = 8183 (intervention = 4049; delayed control 4134)
  3. bChi-square p values except for age (t test p value)
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Trials

ISSN: 1745-6215