The value of post-operative antibiotic therapy after laparoscopic appendectomy for complicated acute appendicitis: a prospective, randomized, double-blinded, placebo-controlled phase III study (ABAP study)

Table 2 Follow-up visits (Spirit figure)

	Screening visit D−1 or D0	Inclusion D−1 or D0	Preoperative period D−1 or D0	Perioperative period	Post-operative period D1–D3	Post-operative FU call D8 post-surgery	Post-operative FU visit D15 ± 7 post- surgery	Post-operative FU visit D30 ± 7 post-surgery
Check on eligibility	✓	✓
Informed consent		✓
Clinical examination		✓	✓	✓				✓
Biological examination		✓	✓	✓		✓^a
ß-hCG test (women of child-bearing age)		✓
Search for AEs		✓	✓	✓				✓
Surgery (laparoscopic appendectomy)				✓
Randomization				✓
Systematic perioperative sample				✓
Post-operative antibiotics for 3 days					✓
Daily follow-up visits				✓
Post-surgery follow-up surgeon						✓	✓	✓

^a blood ion profile, ASAT, ALAT, total bilirubin, indirect bilirubin, alkaline phosphatase, gamma GT, amylase, lipase, CRP, beta HCG, procalcitonin and leucocyte count.
FU follow-up

ISSN: 1745-6215