The effect of supplemental oxygen on perioperative brain natriuretic peptide concentration in cardiac risk patients – a protocol for a prosprective randomized clinical trial

Table 1 Outcomes assessment

	Outcomes	Measurements
Primary	Myocardial function	maxNT-proBNP
Secondary	MINS	maxTnT
	Surgical stress	Copeptin
	Redox stress	sORP, cORP
	Hemodynamic
Exploratory	Cardiac failure	50% increase in NT-proBNP
	Myocardial infarction	ECG change and elevated heart-specific enzymes
	Heart failure requiring intervention	50% NT-proBNP increase and medical treatment
	New onset of cardiac arrhythmias	ECG changes requiring medical treatment and/or electric cardioversion
	Unplanned ICU admission

cORP oxidation-reduction capacity, ECG electrocardiogram, ICU intensive care unit, maxNT-proBNP maximal N-terminal pro-B-type natriuretic peptide, maxTnT maximal troponin T, MINS Myocardial Injury after Noncardiac Surgery, sORP static oxidation-reduction potential

ISSN: 1745-6215