Effectiveness of TOcilizumab in comparison to Prednisone In Rheumatoid Arthritis patients with insufficient response to disease-modifying antirheumatic drugs (TOPIRA): study protocol for a pragmatic trial

Peer Review reports

Original Submission
24 Feb 2020	Submitted	Original manuscript
6 Mar 2020	Reviewed	Reviewer Report - Dennis Lendrem
9 Mar 2020	Reviewed	Reviewer Report - Kirsty Loudon
11 Mar 2020	Author responded	Author comments - Matthijs van der Leeuw
Resubmission - Version 2
11 Mar 2020	Submitted	Manuscript version 2
Publishing
15 Mar 2020	Editorially accepted
5 Apr 2020	Article published	10.1186/s13063-020-04260-y

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