Fig. 2From: Methods for safety and endpoint ascertainment: identification of adverse events through scrutiny of negatively adjudicated eventsPathway for NAE review. Area outlined in red dashed box represents DCRI system for managing NAEs; without implementation of this system, NAEs receive no further consideration and some AEs/SAEs could be missed. AE, adverse event; DCRI, Duke Clinical Research Institute; NAE, negatively adjudicated event; SAE, serious adverse eventBack to article page