Table 2 Selection criteria for WON walled-off necrosis. ^aDiagnosis of WON based on imaging procedures

Inclusion criteria:

Patients eligible for the trial must comply with all of the following at randomization

 • Age 18 years or older

 • Patient with indication (ASGE, Jacobson BC, GIE2005) of drainage of only one type^a related to the symptomatology, as a local complication of previous acute pancreatitis

 • Patient capable of understanding and signing informed consent form

 • Patient understanding the type of study and complying with the follow-up of complementary tests during the study’s duration

Exclusion criteria

 • Pregnancy or breast-feeding

 • Severe coagulation disorder: INR > 1.5 not correctible with administration of plasma and/or platelets < 50,000/mm³

 • Asymptomatic patients, without clinical indication of drainage, except for those with vascular compression involvement

 • Non-identification of solid content during EUS procedure

 • Failure to sign informed consent form

 • Patients with intellectual handicap who are unable to understand the nature and possible consequences of the study, unless there is a competent legal representative

 • Patients unable to adhere to subsequent follow-up requirements

 • Conditions that preclude upper digestive endoscopy, such as stenosis