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Table 1 PICO research question of the arriba-PPI trial

From: Reduction of the long-term use of proton pump inhibitors by a patient-oriented electronic decision support tool (arriba-PPI): study protocol for a randomized controlled trial

PICO-Item

Research question

P (patient)

Patients aged ≥ 18 years regularly using PPIs over ≥ 6 months in primary care

I (intervention)

GPs of enrolled patients with access to the arriba-PPI tool

C (comparison)

GPs of enrolled patients without access to the arriba-PPI tool providing care as usual

O (outcome)

Cumulated defined daily doses of PPI per study patient after 6 months