Table 3 Primary and secondary outcomes at four assessment points (ITT) (non-imputed data)

De Morton Mobility Index (points)

42

63.5 (16.4)

37

69.8 (16.5)

30

71.9 (15.7)

27

70.9 (15.5)

 Lying/sitting

36

21.8 (1.2)

31

20.6 (1.3)

25

19.7 (1.8)

22

19.4 (1.9)

 Uptime

36

1.4 (01.0;1.8)

31

3.2 (1.8;3.7)

25

4.0 (3.0;5.2)

22

4.1 (2.7;5.3)

 Standing

36

1.2 (0.8;1.7)

31

2.5 (1.5;3.1)

25

2.8 (2.4;4.5)

22

3.1 (2.2;4.4)

 Walking

36

0.2 (0.1;0.3)

31

0.5 (0.3;0.8)

25

0.9 (0.4;1.0)

22

0.9 (0.4;1.1)

 Steps (n/day)

36

660 (264;1285)

31

1962 (1114;3219)

25

4147 (1471;4683)

22

3515 (1751;4805)

 Transitions (n up-down/day)

36

50 (41;82)

31

57 (46;78)

25

54 (47;64)

22

56 (43;78)

Isometric knee extension (Nm/kg)

42

0.7 (0.5;0.9)

36

0.7 (0.5;0.9)

29

0.8 (0.6;1.0)

26

0.8 (0.6;0.9)

30-s Sit-to-stand test (reps)

40

5.5 (0 9.5)

37

8 (5;11)

30

9.5 (6;12)

27

10 (5;12)

30-s Sit-to-stand test mod. (reps)^a

11

5 (2;7)

6

6.5 (5;8)

5

4 (4;9)

5

7 (4;8)

Habitual Gait Speed (m/s)

41

0.6 (0.4;0.8)

37

0.7 (0.6;0.9)

30

0.7 (0.6;0.9)

27

0.7 (0.6;0.9)

Hand grip strength (kg)

42

21.5 (10.3)

38

23.5 (9.9)

30

23.5 (10.0)

27

24.0 (10.2)

Barthel Index 20 (points)

42

20 (19;20)

37

20 (19;20)

30

20 (20;20)

27

20 (19;20)

De Morton Mobility Index (points)

43

58.1 (16.2)

28

64.9 (14.2)

26

69.5 (15.7)

25

65.1 (15.8)

 Lying/sitting

25

21.5 (1.5)

25

18.0 (2.1)

19

20.3 (1.7)

17

19.9 (1.9)

 Uptime

25

1.8 (1.1;2.8)

25

3.7 (2.0;4.5)

19

3.4 (2.3;4.2)

17

3.9 (2.7;4.6)

 Standing

25

1.7 (1.0;2.1)

25

3.1 (1.5;4.0)

19

2.7 (1.6;3.7)

17

2.9 (2.1;3.8)

 Walking

25

0.2 (0.1;0.6)

25

0.5 (0.3;0.6)

19

0.6 (0.5;0.9)

17

0.6 (0.4;0.9)

 Steps (n/day)

25

754 (187;2352)

25

1961 (1370;2791)

19

2800 (1607;3509)

17

2319 (1300;4092)

 Transitions (n up-down/day)

25

47 (26;68)

25

46.7 (38;65)

19

51 (36;64)

17

57 (39;69)

Isometric knee extension (Nm/kg)

40

0.6 (0.5;0.8)

27

0.6 (0.4;0.8)

26

0.57 (0.44;0.75)

23

0.6 (0.5;0.7)

30-s Sit-to-stand test (reps)

39

6 (0;9)

28

8.5 (3.5;10)

26

7.5 (5;12)

24

6 (3;11.5)

30-s Sit-to-stand test mod (reps)^a

10

7.5 (4;9)

4

5.5 (3.5;7)

3

7 (6;9)

4

6 (4;8.5)

Habitual Gait Speed (m/s)

41

0.6 (0.5;0.8)

29

0.7 (0.5;0.8)

26

0.64 (0.54;0.87)

25

0.6 (0.5;0.8)

Hand grip strength (kg)

43

21.1 (8.7)

29

21.8 (8.9)

26

22.4 (8.7)

25

21.8 (8.4)

Barthel Index 20 (points)

43

19 (18;20)

29

20 (19;20)

26

20 (19;20)

25

20 (19;20)